RUNX1 mutations are rare in chronic phase polycythaemia vera
نویسندگان
چکیده
منابع مشابه
Peripheral gangrene in polycythaemia vera.
well account for the phonocardiographic features of extreme variability of the A2-OC interval and the intermittent absence of the OC. The systolic murmur was in keeping with mitral reflux with its rate related variability. In a very ill patient with a malfunctioning mitral Starr-Edwards prosthesis we feel that the phonocardiographic findings can be a useful bedside adjunct to the physician and ...
متن کاملJoint Complaints in Polycythaemia Vera.
The reported incidence of gout and hyperuricaemia in polycythaemia vera has varied in different series. Thus Tinney, Polley, Hall, and Giffin (1945) reported clinical gout in 4 7 per cent. of 168 cases, Videbaek (1950) in 9 per cent. of 125 cases, and Lawrence, Berlin, and Huff (1953) in 7 per cent. of 159 patients, and unspecified arthritis in a further 14 per cent. On the other hand, Wasserma...
متن کاملCo-existent chronic lymphatic leukaemia with polycythaemia vera.
A patient presenting with chronic lymphocytic leukaemia and iron deficiency anaemia who, following oral iron therapy, developed the clinical and pathological features of polycythaemia vera is reported. The relationship between these two diseases when co-existing is discussed.
متن کاملReno-vascular disease in polycythaemia rubra vera.
Hypertension and polycythaemia rubra vera commonly occur in the same patient. This is regarded as coincidence and the hypertension does not respond to correction of polycythaemia. We report a case of renal artery stenosis occurring simultaneously with polycythaemia rubra vera and suggest that renovascular occlusive disease should be excluded in such patients with refractory hypertension.
متن کاملMasked polycythaemia vera is genetically intermediate between JAK2V617F mutated essential thrombocythaemia and overt polycythaemia vera
Polycythaemia vera (PV) can be defined as a myeloproliferative neoplasm (MPN) with erythrocytosis and JAK2V617F (or an equivalent marker of clonality). While these simple criteria are sufficient for most cases of overt PV, an estimated 10–15% of PV patients do not have an elevated haemoglobin concentration (Hb) and may mimic JAK2-positive essential thrombocythaemia (ET). This poses a problem fo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2011
ISSN: 0007-1048
DOI: 10.1111/j.1365-2141.2011.08589.x